27 November 2017 to 1 December 2017
KNUST
Africa/Accra timezone

A support vector machine model for cancer detection and patient survival using the transcriptome datasets

29 Nov 2017, 14:30
15m
Amonoo-Neizer Conference Center (KNUST)

Amonoo-Neizer Conference Center

KNUST

University Post Office, Private Mail Bag KNUST Kumasi-Ghana

Speaker

Mr Andrews Adu

Description

Cancer is a deadly disease worldwide and an early diagnosis is essential to a successful treatment and the development of effective therapeutic strategies. Previously, approaches for diagnosis are expensive and most often are able to detect the disease when it has already grown. Moreover, analytical and computational methods are complicated by the heterogeneity of cancer cell phenotypes that exist within a single tumor, which drives metastasis, resistance to treatment, and eventually, recurrence.
However, with the recent advent of sequencing technologies (RNA-Seq) which are able to monitor the activities of the cells, revealing molecular aberrations in the cells and gene expression levels, large-scale datasets have been produced. The analysis of these datasets could reveal diseases initiating genes in the cells.
Notably, not all faulty genes lead to cancer therefore, we seek to identify some of these key genes and develop a support vector classifier that will learn from these key genes and use it to predict new instances of the disease.

Primary author

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